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Mechanistically, TH have been shown to suppress hepatic fibrosis by inhibiting SMAD2/3 phosphorylation within the TGF- signaling pathway, thereby downregulating fibrosis-associated gene expression (34)

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Supplementary Data 1 (download XLSX Source data for Supplementary Fig

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Warfarin : Although no direct pharmacokinetic interaction exists, changes in diet, weight, or gastrointestinal function during semaglutide treatment could affect warfarin requirements